StreetWorks Opioid Safety


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Nasal Naloxone

Intramuscular Naloxone

A pink drawn heart with two red hands making a heart inside. The text reads "Harm Reduction Saves Lives"
“Harm Reduction Saves Lives” by artist Malicia

Naloxone is a life-saving medication used to reverse an opioid overdose. Naloxone—sometimes referred to by its brand name “Narcan”—works as an opioid-antagonist, binding to opioid receptors on the brain stem and reducing the effects of opioids like fentanyl, heroin, morphine, and oxycodone.

In an overdose, a person’s breathing slows or stops; naloxone can restore normal breathing within 2 to 3 minutes. However, naloxone’s power to reverse an overdose is temporary. It stops working between 30 to 90 minutes after being used, so it is critical to call 911 when someone has overdosed.

It comes in both injectable (intramuscular) and nasal spray forms. Legal to possess, and available without a prescription, anyone can carry naloxone to protect their loved ones and their community. As it has no effect on people who have not overdosed, it can be given safely to anyone who is suspected to have overdosed.

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